Gunjan Singh, PhD, a Postdoctoral Research Associate in the Larschan Lab was recently awarded the 2023 Glenn Foundation for Medical Research Postdoctoral Fellowships in Aging Research. This program was developed to provide support for postdoctoral fellows (MD, MD/PhD and PhD) who specifically direct their research towards basic aging mechanisms and/or translational findings that have direct benefits to human aging and healthspan.
Recently, Dr. Jill Kreiling and her group at the Center on the Biology of Aging at Brown University proposed a creative and innovative solution to the problem that would not only allow for fast, cost-effective AD testing but also provide a framework for ADRD rapid diagnosis and early prevention.
In their latest publication in Genetics, Dr. Marc Tatar and his team identified a new gene mutation that has promising applications for aging research. This mutation is in the insulin receptor, which is part of the long-studied insulin/insulin-like growth factor (IGF) pathway thought to play a critical role in aging.
Led by principal investigator John Sedivy, a multi-university effort will build on recent discoveries about mechanisms of aging to understand causes and potential treatments for neurodegenerative diseases.
The newly established NIH Common Fund SenNet Program was created to comprehensively uncover the characteristics of senescent cells across the body, across various states of human health, and across lifespan. The goal of SenNet is to provide publicly accessible atlases of senescent cells, the differences among them, and the molecules they secrete, using data collected from multiple human and model organism tissues.
Brown researcher John Sedivy, lead author of a sweeping review article about transposons, explains what these mobile genetic elements are, how they are more harmful than benign and where their weaknesses may lie.