Cold Spring Harbor Laboratory recently hosted Jill Kreiling, Ph.D. for the Mechanisms of Aging meeting on September 26th. Follow this link to view her full presentation!
Neuropeptide F (NPF) produced in the Drosophila gut is an insulin-regulatory hormone (incretin) that is secreted into adult circulation in response to feeding and diet. Suppression of gut NPF extends Drosophila longevity, as does knockdown of NPF receptors at the insulin-producing medial neurosecretory cells in the brain that control the titer of juvenile hormone (JH). Gut hormones and brain insulin regulate lifespan because they control JH titer, which itself is the master endocrine regulator of Drosophila aging. Gut NPF modulates Drosophila aging through the integration of nutrient sensing, insulin signaling, and JH. Given the role of incretin-mimetic drugs to treat diabetes and obesity, it may be time to consider how incretin analogs could impact human aging.
June 3, 2024 Nature Reviews Molecular Cell Biology
The Center on the Biology of Aging is recruiting multiple postdoctoral positions. Eligible candidates should apply by April 1, 2024 via the Interfolio link.
Gunjan Singh, PhD, a Postdoctoral Research Associate in the Larschan Lab was recently awarded the 2023 Glenn Foundation for Medical Research Postdoctoral Fellowships in Aging Research. This program was developed to provide support for postdoctoral fellows (MD, MD/PhD and PhD) who specifically direct their research towards basic aging mechanisms and/or translational findings that have direct benefits to human aging and healthspan.
Recently, Dr. Jill Kreiling and her group at the Center on the Biology of Aging at Brown University proposed a creative and innovative solution to the problem that would not only allow for fast, cost-effective AD testing but also provide a framework for ADRD rapid diagnosis and early prevention.
We are pleased to welcome Dr. Carlos Giovanni (Gio) Silva-García, an esteemed scientist from Dr. William Mair’s lab at Harvard and an expert on genetics and epigenetics of aging!
The Webb Lab at Brown University’s Center on the Biology of Aging publishes groundbreaking work on human brain aging, discovering novel sex-specific differences in the hypothalamus