Division of Biology and Medicine
Center on the Biology of Aging

Stephen Helfand, MD

Associate Director for Research, Professor, Department of Molecular Biology, Cell Biology and Biochemistry
Stephen_Helfand@brown.edu
Research Profile
Research Interests Genetic control of longevity, calorie restriction, sirtuins, insulin/IGF signaling

Biography

Research Interests: Genetic control of longevity, calorie restriction, sirtuins, insulin/IGF signaling

We study the molecular mechanisms that underly aging, longevity and neurodegeneration. We are exploiting Drosophila as a model system, and more recently mice, and we use genetic approaches to study diet restriction, sirtuins and the role of chromatin homeostasis in maintaining youthfulness.