Division of Biology and Medicine
Center on the Biology of Aging

Qian Chen, PhD

Professor, Department of Orthopaedics
Research Interests Skeletal development and aging, osteoarthritis, role of senescent cells in skeletal aging, mechano-transduction
Research We study molecular mechanisms of cell aging and senescence that lead to skeletal system degenerative diseases in humans. Specifically, we use the osteoarthritic joint cartilage as our model system to analyze how senescence-associated cell transitions

Biography

Research Interests:  Skeletal development and aging, osteoarthritis, role of senescent cells in skeletal aging, mechano-transduction

We study molecular mechanisms of cell aging and senescence that lead to skeletal system degenerative diseases in humans. Specifically, we use the osteoarthritic joint cartilage as our model system to analyze how senescence-associated cell transitions and interactions result in tissue pathology.