Division of Biology and Medicine
Center on the Biology of Aging
Qian Chen, PhD
Professor, Department of Orthopaedics
Research Interests
Skeletal development and aging, osteoarthritis, role of senescent cells in skeletal aging, mechano-transduction
Research
We study molecular mechanisms of cell aging and senescence that lead to skeletal system degenerative diseases in humans. Specifically, we use the osteoarthritic joint cartilage as our model system to analyze how senescence-associated cell transitions
Biography
Research Interests: Skeletal development and aging, osteoarthritis, role of senescent cells in skeletal aging, mechano-transduction
We study molecular mechanisms of cell aging and senescence that lead to skeletal system degenerative diseases in humans. Specifically, we use the osteoarthritic joint cartilage as our model system to analyze how senescence-associated cell transitions and interactions result in tissue pathology.