Center on the Biology of Aging

Research Interests: Mechanobiology, extra-cellular matrix dynamics, senescence-associated exosomes, TGF-B signaling, fibrosis

We study mechanisms by which senescent cells alter tissue microenvironments to promote cancer and age-related disease. We are investigating the physical and molecula alterations in senescent cells that contribute to extracellular matrix remodeling, tissue stiffening, and fibrosis.