Division of Biology and Medicine
Center on the Biology of Aging

Marc Tatar, PhD

Associate Director of MBoA Training Grant, Professor of Biology, Department of Ecology and Evolutionary Biology
Research Interests Demography, evolution and genetics of aging, endocrine control of longevity, insulin/IGF signaling, innate immunity

Biography

Demography, evolution and genetics of aging, endocrine control of longevity, insulin/IGF signaling, innate immunity, Drosophila model system

Dr. Tatar is widely recognized for key studies to understand the mechanisms of longevity control through the explicit analysis of age-specific mortality. Trained as an ecologist, Dr. Tatar initially worked on many natural species from beetles, to butterflies, grasshoppers and baboons. Aiming to understand the mechanisms of aging, Dr. Tatar subsequently trained in Drosophila genetics and then established a group at Brown University with the fly as its model. His work has established benchmarks on the effects of insulin/IGF signaling on longevity. Endocrine signaling through lipid hormones is an additional focus of Dr. Tatar's group, which will increase understanding of the age-dependent decline of innate immunity, cardiac function, and reproduction. Dr. Tatar also leads a multi-site study that is mapping the genetic factors responsible for female reproductive aging in a nonhuman primate model system, the baboon. Dr. Tatar was the founding editor-in-chief of Aging Cell and thereafter served two years on the Board of Reviewing Editors at Science. Since joining Brown University in 1997, Dr. Tatar has been continuously funded by the National Institute on Aging. Dr. Tatar has received both a New Investigator and Senior Investigator Award from the Ellison Medical Foundation.