Center on the Biology of Aging

Research Interests: Chromatin homeostasis, cell senescence, retrotransposable elements, interferon, neurodegenerative disease therapy.

We study mechanisms that lead to cell senescence, the epigenetic changes that occur in senescent cells, and the consequences of their accumulation in aging tissues. We discovered that retro transposons are activated in senescence and are exploring their inhibition as therapy for age-related diseases.