Center on the Biology of Aging

Research Interests: Brain development, maintenance, Mendelian neurodegenerative diseases, dysfuntion of endolysosomal system in aging.

I work on mechanisms that regulate brain development and maintenance,using functional analysis of mutations that lead to neurodegeneration (autism, Christianson syndrome). We are interested in the dysfunction of the endolysosomal system, a feature in many neurodegenerative disorders.